By Gert Lubec
A new promising animal version of DS is pronounced and this opens new possibilities to check pathomechanisms and pharmacological ways because it is greater than tricky to hold out reports in people and the medical good points are hugely variable. when it comes to biology, phone cycle and stem telephone reports and by way of biochemistry, relevance of reviews on a particular protein kinase, channels, transporters, superoxide dismutase, antioxidant process, chromosome meeting issue and different very important organic constructions are supplied. And back, the gene dosage speculation is addressed and even though the majority of chromosome 21 gene items is unchanged in fetal DS mind, a couple of particular chromosome 21 encoded buildings together with transcription components are certainly overexpressed even supposing findings in fetal DS are diversified from these in grownup DS mind whilst Alzheimer-like neuropathology supervenes.
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Advances in Down Syndrome Research (Journal of Neural Transmission. Supplementa) by Gert Lubec